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Exercises for the General, Organic, & Biochemistry Laboratory, 2e

William G. O'Neal
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This book is customizable for courses with annual enrollments of 50 students or more. 

This full-color, comprehensive, affordable manual is intended for a one-semester general, organic, and biochemistry course, preparatory/basic chemistry course, liberal arts chemistry course, or allied health chemistry course. The procedures are written with the goal of simplifying a complicated and often challenging subject for students by applying concepts to everyday life.

The first half of the lab manual covers general topics such as chemical and physical properties, elements of the periodic table, types of bonds, empirical formulas, and reaction stoichiometry. These labs form the foundation for future labs, which cover the basics of organic and biological chemistry. Experiments include the classification of organic compounds and the determination of biomolecules.

By the end of this course, students should have a solid understanding of the basic concepts of chemistry, which will give them confidence as they embark on various allied health careers.


About this Product


  • Initiate the study of basic concepts in the general, organic, and biochemistry laboratory by reading through concise introductory material and answering pre-lab questions that familiarize students with the concepts presented in each exercise. The inclusion of color photography and high-quality art promotes engagement and comprehension of the more difficult concepts.
  • Investigate the mysteries of matter by following the clearly written procedures and recording data and observations on the provided data sheets. Common techniques are reviewed as needed in Technique Tips boxes to reinforce the development of basic laboratory skills. OSHA pictograms, and Lab Safety boxes are provided to help students understand any risks associated with specific chemicals and equipment.
  • Integrate knowledge of each laboratory topic by making sense of the data that has been collected. Reflective Exercises galvanize critical thinking and scientific analysis skills to take shape as students make connections between what has been learned and practiced in the hands-on lab and how this knowledge can be applied to a relevant, real-world context.

About the Author

William G. O'Neal

William G. (Will) O’Neal is a faculty member in the Chemistry Department at the University of Richmond, where he directs the organic chemistry laboratory curriculum. He was previously a chemistry instructor and physical sciences department head at Coastal Carolina Community College in Jacksonville, North Carolina. He received a Ph.D. in chemistry from Dartmouth College, where his research focused on the development of new synthetic routes to macrocyclic tetrapyrroles of the chlorin and bacteriochlorin classes. Will served as an American Chemical Society Congressional Fellow from 2008 to 2009 and subsequently worked as a congressional staffer. He and his family reside in Richmond, Virginia.

What's New in this Edition

New to this edition of Exercises for the General, Organic, & Biochemistry Laboratory, 2e

  • There is a new lab on the scientific method (Lab 1).
  • Measurements and density have been divided into two separate labs (Labs 2 and 3).
  • A third reaction was added to the hydrocarbon lab (Lab 12).
  • The lab on acid-base extraction with replaced with a lab on titration (Lab 18).
  • A lab on proteins was added (Lab 21).
  • An analysis component was added to the lab on DNA extraction (Lab 23).

Table of Contents


Laboratory Safety

Lab 1: Be Methodical: Think Like a Chemist

Lab 2: It’s Significant: Laboratory Measurements and Units

Lab 3: Be Precise: Density and Measurement Precision

Lab 4: The More Things Change: Chemical and Physical Properties

Lab 5: Counting Calories: Calorimetry and Specific Heat

Lab 6: All in the Family: Elements and the Periodic Table

Lab 7: Eat Your Wheaties: Nutritional Minerals in Cereal

Lab 8: Puzzled?: Ionic and Covalent Bonding Patterns

Lab 9: Tried and True: Formula of a Compound

Lab 10: Don’t Lose Your Balance: Verification of Reaction Stoichiometry

Lab 11: Lab Is Such a Headache: Synthesis of Aspirin

Lab 12: Skeletons and Suffixes: Hydrocarbon Isomerism and Bond Reactivity

Lab 13: How Sweet It Is: Structures of Carbohydrates

Lab 14: Take Your Medicine: Thin Layer Chromatography of Analgesic Drugs

Lab 15: A Lot of Hot Air: Simple Gas Laws in Action

Lab 16: It’s No Problem: All About Solutions

Lab 17: True Colors: Acids, Bases, Buffers, and pH Indicators

Lab 18: Pretty in Pink: Titration of Vinegar

Lab 19: Clean It Up: Formation and Evaluation of Soap

Lab 20: Why It Does a Body Good: The Components of Milk

Lab 21: The Blue-Green Protein: Denaturation of Phycocyanin

Lab 22: Got Milk Sugar?: Lactase and Enzyme Activity

Lab 23: Blueprint of a Strawberry: DNA Extraction